R & D / KILO LAB
R & D / Kilo Lab
Research and Development (R&D) department plays a crucial role in ensuring efficient, cost-effective, and scalable production processes. Below are the key responsibilities of the R&D department:
Process Development:
- Route Selection: R&D is responsible for identifying the most efficient synthetic route for manufacturing the API intermediates, considering factors such as yield, safety, and environmental impact.
- Optimization: Once a synthetic route is selected, R&D works to optimize reaction conditions (temperature, pressure, solvents, catalysts) to maximize yield and purity while minimizing costs and waste.
New Product Development:
- Feasibility Studies: R&D conducts feasibility studies to explore the possibility of manufacturing new API intermediates, including small-scale laboratory experiments to validate new concepts.
- Scaling Up: After developing a process in the lab, R&D works on scaling it up for larger production, addressing challenges related to scalability, equipment compatibility, and quality.
Technology Transfer:
- R&D collaborates with the manufacturing and production teams to ensure the seamless transfer of newly developed processes from the lab scale to full-scale production. This involves providing detailed process descriptions, equipment requirements, and handling guidelines.
Cost Reduction & Process Improvements:
- R&D continually seeks ways to reduce production costs by improving process efficiency, reducing raw material consumption, and identifying cheaper or greener alternatives to solvents or reagents.
- They may also work on process intensification to make the manufacturing process faster and more efficient.
Regulatory Support:
- R&D is responsible for generating technical documentation needed for regulatory submissions, including information about synthetic routes, impurities, and its formation & its removal from the process.
- They assist with preparing Common Technical Documents (CTDs).
Environmental and Safety Compliance:
- R&D plays a key role in ensuring that manufacturing processes are environmentally friendly and safe. They work on minimizing waste generation, handling hazardous materials safely, and ensuring compliance with environmental regulations.
Problem-Solving and Troubleshooting:
- In case of production issues, such as deviations or product quality problems, R&D steps in to investigate root causes and develop solutions to resolve them, ensuring the process remains robust and reliable.
Collaboration with Quality and Regulatory Teams:
- R&D works closely with Quality Assurance (QA) and Quality Control (QC) teams to ensure that the developed processes meet all required quality standards.
- They also collaborate with regulatory teams to ensure all process changes are documented and comply with regulatory requirements.
By performing these functions, the R&D department ensures that the manufacturing process is innovative, efficient, compliant with regulations, and capable of consistently producing high-quality API intermediates.
Research and Development working
on below areas
- To develop technologies for new products.
- Define Route of Synthesis and making ROS, list of Raw Materials, Catalyst, Solvents, Impurities in finished products.
- Design process in such a way that customer specification is achieved.
- To establish processes in laboratory for products to be scaled up.
- Products development for improving quality and environment.
- Simplified process.
- Versatile and flexible manufacturing modules with all the lab wares.
Research & Development, Kilo Lab & Pilot Plant Fully equipped with glass assembly-reactor & SS reactors
- Area (Sq. Feet) 11000 Square Feet.
- R&D, Kilo Lab : 4 Nos.
- Total Operating Volume 4 KL
- Operating Temperature -70 to 220 deg C
- Operating Pressure up to 0-35 kg/cm2
- Operating Vacuum up to 1.0 mm Hg
Research & Development, Kilo Lab & Pilot Plant have following Equipments
- 20, 50 Lit Glass Assemblies – 36 Nos.
- 5, 100 Lit Gas Induction Reactors - 2 Nos.
- 250 Lit Glass lined Reactors - 2 No.
- 500 Lit SS-316 Reactors - 5 No.
- 20, 50 and 200 Litre High Vacuum Distillation Assemblies Fractionating column – 9 Nos.
- 24 “ SS-316 Centrifuges – 4 Nos.
- SS-316 Sparkler Filters – 4 Nos.
- SS-316 Tray Dryers – 4 Nos.
- Water Ejectors – 16 Nos.
- High Vacuum Pump – 28 Nos.
- HDPE Scrubbers – 2 Nos.
- Try Dryers : 6,12, 24 Nos.
Pioneering Chemical Excellence with Cutting-Edge Facilities.
AllChem provides cutting-edge facilities for research, manufacturing, and quality assurance, ensuring innovation, safety, and reliability in every solution.